Kommende arrangementer

Generalforsamling i DSP og foredrag ved sognepræst Kathrine Lilleør
Sted: Gentofte Hotel
Dato: 13. marts 2018
Tid: 18:00 - 21:00

Dansk Selskab til Studiet af Parodontologi blev stiftet 23. januar 1953, som den første parodontologiske forening i Danmark.


Formålet med foreningen er at styrke kendskabet til sygdomsudvikling og behandling af marginal parodontitis samt peri-implantitis.
Foreningen har tandlæger som medlemmer og tandplejere som associerede medlemmer, hovedsageligt fra Danmark. Foreningen har i dag små 200 aktive medlemmer.

Foreningen afholder årligt 4 foredrag samt en generalforsamling. Inden hvert foredrag er der en sammenkomst med et lille traktement. Ved generalforsamling, som afholdes i marts/april, er der en middag.

Impact of Periodontitis Case Criteria: A Cross-Sectional Study of Lifestyle

Kongstad J1Enevold C2Christensen LB1Fiehn NE3Holmstrup P1.

J Periodontol. 2017 Jun;88(6):602-609. doi: 10.1902/jop.2017.160426. Epub 2017 Jan 27.

BACKGROUND:

Associations of risk factors/indicators with periodontitis may depend on the included case criterion. The objective of the current study is to evaluate differences in outcome by applying five periodontitis case definitions for cross-sectional associations with lifestyle factors among participants of the Danish Health Examination Survey (DANHES).

METHODS:

A total of 4,402 adults aged 18 to 96 years from the general health examination of DANHES had a periodontal examination consisting of half-mouth registration at six sites per tooth including probing depth (PD) and clinical attachment level (CAL). Periodontitis was defined according to severe periodontitis, European Workshop of Periodontology (EWP)-specific, meanCAL ≥2.55 mm, CAL-tertile, and PD-CAL definitions. Multivariable logistic regression models fitted the association of age, sex, smoking status, diabetes mellitus, educational level, alcohol consumption, body mass index, physical activity, body fat percentage, waist circumference, triglycerides, total cholesterol, and C-reactive protein with periodontitis.

RESULTS:

Number of cases captured by the five periodontitis case definitions ranged from 337 (9.2%) to 1,136 (31.0%). A total of 224 participants were defined as periodontitis cases by all five criteria. Analyses on 3,665 participants with complete data revealed statistically significant associations of age and smoking with all periodontitis case definitions and of male sex with severe periodontitis and EWP-specific definitions. Educational level (two lowest groups) was related to three periodontitis criteria. Among obesity and hyperlipidemia measures no factors were related to periodontitis.

CONCLUSION:

Regression analyses showed little difference in odds ratio across the five periodontitis case definitions; however, the level of significance did show some variation.

 

Kilde: PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28128681

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Metagenomic and metatranscriptomic analysis of saliva reveals disease-associated microbiota in patients with periodontitis and dental caries

Belstrøm D#1Constancias F#2Liu Y2Yang L2Drautz-Moses DI2Schuster SC2Kohli GS2Jakobsen TH3Holmstrup P1Givskov M2,3.

NPJ Biofilms Microbiomes. 2017 Oct 2;3:23. doi: 10.1038/s41522-017-0031-4. eCollection 2017

The taxonomic composition of the salivary microbiota has been reported to differentiate between oral health and disease. However, information on bacterial activity and gene expression of the salivary microbiota is limited. The purpose of this study was to perform metagenomic and metatranscriptomic characterization of the salivary microbiota and test the hypothesis that salivary microbial presence and activity could be an indicator of the oral health status.

Stimulated saliva samples were collected from 30 individuals (periodontitis: n = 10, dental caries: n = 10, oral health: n = 10). Salivary microbiota was characterized using metagenomics and metatranscriptomics in order to compare community composition and the gene expression between the three groups.

Streptococcus was the predominant bacterial genus constituting approx. 25 and 50% of all DNA and RNA reads, respectively. A significant disease-associated higher relative abundance of traditional periodontal pathogens such as Porphyromonas gingivalis and Filifactor alocis and salivary microbial activity of Falocis was associated with periodontitis. Significantly higher relative abundance of caries-associated bacteria such as Streptococcus mutans and Lactobacillus fermentum was identified in saliva from patients with dental caries. Multiple genes involved in carbohydrate metabolism were significantly more expressed in healthy controls compared to periodontitis patients.

Using metagenomics and metatranscriptomics we show that relative abundance of specific oral bacterial species and bacterial gene expression in saliva associates with periodontitis and dental caries. Further longitudinal studies are warranted to evaluate if screening of salivary microbial activity of specific oral bacterial species and metabolic gene expression can identify periodontitis and dental caries at preclinical stages.

Kilde: PubMed: https://www.ncbi.nlm.nih.gov/pubmed/28979798

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