Kommende arrangementer

Prognose for implantatbehandling
Sted: Gentofte Hotel
Dato: 26. oktober 2017
Tid: 17:30 - 20:00

Parodontitis ætiologi, forebyggelse og behandling i lyset af mikrobiomkonceptet
Sted: Gentofte Hotel
Dato: 21. november 2017
Tid: 17:30 - 20:00

Dansk Selskab til Studiet af Parodontologi blev stiftet 23. januar 1953, som den første parodontologiske forening i Danmark.


Formålet med foreningen er at styrke kendskabet til sygdomsudvikling og behandling af marginal parodontitis samt peri-implantitis.
Foreningen har tandlæger som medlemmer og tandplejere som associerede medlemmer, hovedsageligt fra Danmark. Foreningen har i dag små 200 aktive medlemmer.

Foreningen afholder årligt 4 foredrag samt en generalforsamling. Inden hvert foredrag er der en sammenkomst med et lille traktement. Ved generalforsamling, som afholdes i marts/april, er der en middag.

Salivary cytokine levels in early gingival inflammation

Belstrøm D1Damgaard C1,2Könönen E3Gürsoy M3Holmstrup P1Gürsoy UK3.

J Oral Microbiol. 2017 Aug 11;9(1):1364101. doi: 10.1080/20002297.2017.1364101. eCollection 2017.

Abstract

Salivary protein levels have been studied in periodontitis. However, there is lack of information on salivary cytokine levels in early gingival inflammation. The aim of this study was to determine salivary levels of vascular endothelial growth factor (VEGF), interleukin (IL)-8, monocyte chemoattractant protein (MCP)-1, IL-1β, and IL-1 receptor antagonist (IL-1Ra) in gingival inflammation. Twenty-eight systemically and orally healthy nonsmokers abstained from oral hygiene protocols for 10 days. After that, self-performed cleaning was resumed for 14 days. Plaque and gingival indexes were measured, and saliva samples were collected at days 1, 4, 7, 10, and 24. Salivary cytokines were detected with Luminex®-xMAP™. Salivary IL-1β, IL-1Ra, and VEGF levels decreased after 10 days’ development of experimental gingivitis and reached baseline levels at the end of the 2-week resolution period. Salivary IL-8 levels decreased and remained low during development and resolution of experimental gingivitis. Initial inflammation in gingival tissues is associated with a decrease in inflammatory cytokines in saliva. Further studies are needed to evaluate if inflammatory cytokines bind to their functional receptors within the gingival tissue during early gingivitis, which may limits their spillover to the gingival crevice and ultimately saliva.

KEYWORDS:

Gingivitis; human; interleukin-1 receptor antagonist; interleukin-1β; interleukin-8; monocyte chemoattractant protein-1; vascular endothelial growth factor

https://www.ncbi.nlm.nih.gov/pubmed/28839521

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Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

Holmstrup P1Damgaard C1,2Olsen I3Klinge B4,5Flyvbjerg A6Nielsen CH1,2Hansen PR1,7.

J Oral Microbiol. 2017 Jun 14;9(1):1332710. doi: 10.1080/20002297.2017.1332710. eCollection 2017.

Abstract

Increasing evidence has suggested an independent association between periodontitis and a range of comorbidities, for example cardiovascular disease, type 2 diabetes, rheumatoid arthritis, osteoporosis, Parkinson’s disease, Alzheimer’s disease, psoriasis, and respiratory infections. Shared inflammatory pathways are likely to contribute to this association, but distinct causal mechanisms remain to be defined. Some of these comorbid conditions may improve by periodontal treatment, and a bidirectional relationship may exist, where, for example, treatment of diabetes can improve periodontal status. The present article presents an overview of the evidence linking periodontitis with selected systemic diseases and calls for increased cooperation between dentists and medical doctors to provide optimal screening, treatment, and prevention of both periodontitis and its comorbidities.

KEYWORDS:

Alzheimer’s disease; Parkinson’s disease; Periodontitis; cardiovascular disease; comorbidity; low-grade inflammation; osteoporosis; periodontal disease; pneumonia; psoriasis; rheumatoid arthritis; type 2 diabetes

https://www.ncbi.nlm.nih.gov/pubmed/28748036

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